Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

Protein C Activity

LOINC codes
27819-2
Tests that measure Protein C Activity
Quest Diagnostics 9

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, Protein C Activity 1777

PopulationInterval
0-15 yearsNo reference range available
≥16 years70-180 % normal

Quest Diagnostics test catalog, 1777

Tests

Check the catalog code, specimen, method and preparation for every test that measures Protein C Activity. Select up to five tests to compare them side by side.

Quest Diagnostics 9 tests

Single-analyte tests

  • Protein C Activity 1777

    Plasma · Fasting not stated · Turnaround Report available: 4 days

    Method and collection
    Method
    Clotting Assay
    Collection
    ⁠⁠⁠⁠⁠⁠⁠Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet poor plasma into a new transport tube. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and ship on dry ice.
    Quest Diagnostics catalog page

Panels that include this biomarker

  • Protein C Activity and Antigen 8757

    2 analytes · Plasma · Fasting not stated

    Method and collection
    Method
    Clotting Assay • Immunoassay (IA)
    Collection
    Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
    Reference notes
    Protein C Activity 0-15 years | No reference range available ≥16 years | 70-180 % normal Protein C Antigen 0-15 years | No reference range available ≥16 years | 70-140 % normal
    Quest Diagnostics catalog page

  • Protein C and Protein S, Functional 39457

    2 analytes · Plasma · Fasting not stated

    Method and collection
    Method
    Clotting Assay
    Collection
    Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
    Reference notes
    Protein C Activity 0-15 years | No reference range available ≥16 years | 70-180 % normal Protein S Activity Males | 70-150 % normal Females | 60-140 % normal
    Quest Diagnostics catalog page

  • Thrombophilia Screen II, Inherited 11327

    4 analytes · Plasma · Fasting not stated

    Method and collection
    Method
    Polymerase Chain Reaction & Detection • Chromogenic Substrate • Clotting Assay • Immunoturbidimetric Reflex: Fluorescent Microspheres • Oligonucleotide Ligation Assay • Polymerase Chain Reaction (PCR)
    Collection
    This panel requires platelet-poor plasma and whole blood. Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice. Whole blood: Preferred shipping temperature is frozen, but room temperature shipping is acceptable.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Thrombosis Panel 11051

    4 analytes · Plasma · Fasting not stated

    Method and collection
    Method
    Clotting Assay • Clot Detection • Chromogenic Substrate • RVVT-based Assay (Clot-based)
    Collection
    Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/uL) Freeze immediately and ship on dry ice.
    Reference notes
    See individual tests
    Quest Diagnostics catalog page

  • Venous Thrombosis Hypercoagulability Panel with Reflex 11475

    10 analytes · Plasma · Fasting not stated

    Method and collection
    Method
    Chromogenic Clotting Assay • Enzyme Immunoassay (EIA) • Immunoturbidimetric Immunoassay • Polymerase Chain Reaction and Detection
    Collection
    Whole blood sample is for the Factor V Mutation Analysis and Prothrombin (Factor II) Mutation Analysis. Platelet-poor plasma is for remaining tests. Platelet-poor plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500 x g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into six plastic vials. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice. Note: Storage of whole blood at refrigerated temperatures prior to processing may lead to cryoprecipitate formation and falsely low Factor VIII and von Willebrand Factor studies.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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