Biomarkers · Chemical
SRA, Low Dose Heparin
- Primary unit
- %
- LOINC codes
- 77728-4
- Tests that measure SRA, Low Dose Heparin
- Labcorp 1
Tests
Check the catalog code, specimen, method and preparation for every test that measures SRA, Low Dose Heparin. Select up to five tests to compare them side by side.
Labcorp 1 test
Panels that include this biomarker
Heparin-dependent Platelet Antibody (Serotonin Release Assay) 150018
2 analytes · Serum · Fasting not stated · Turnaround 3 - 7 days
Labcorp catalog pageMethod and collection
- Method
- The SRA employs washed donor platelets and detects their activation by measuring the release of endogenous serotonin induced by addition of patient serum. The serotonin levels are measured by a highly sensitive liquid chromatography/tandem mass spectroscopy method. Therapeutic levels of heparin included in the assay mix allow for the formation of PF4/heparin complexes on the donor platelet surface to provide an antigen target for the HIT antibodies. The specificity of the assay is increased by assessing the inhibition of platelet activation by adding heparin in excess, thus proving the heparin dependency of the serotonin release.
- Collection
- Transfer serum to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
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1 test: codes, specimens, methods, preparation and reference intervals.
LOINC 77728-4
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for SRA, Low Dose Heparin
Registered studies that measure SRA, Low Dose Heparin, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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