Biomarkers · Chemical
Thyroid Peroxidase Antibody
A thyroid antibody test measures the level of thyroid antibodies in a sample of your blood to check for an autoimmune thyroid disease. Your thyroid is a small, butterfly-shaped gland in your neck.
Thyroid Antibody Tests, MedlinePlus, National Library of Medicine
- Also listed as
- TPO, Thyroid Peroxidase Ab
- Primary unit
- IU/mL
- LOINC codes
- 8099-4
- Tests that measure Thyroid Peroxidase Antibody
- Quest Diagnostics 9, Labcorp 6
Ranges
Compare the reference ranges labs publish with guideline targets, diagnostic cut-offs, study-based ranges and practitioner targets. Move across the rows to check a value against each range, and open a source from the legend. How to read these ranges
Thyroid Peroxidase Antibody, IU/mL
- Lab reference ranges2 labs
All 2 published ranges, with sources
Lab reference ranges
Quest, all agesbelow 9 IU/mL
All ages
Published as below 9 IU/mL.
Quest Diagnostics Test Directory, Thyroid Peroxidase Antibodies (TPO) (5081), 2025
Labcorp, adults over 190 to 34 IU/mL
Adults over 19
Labcorp test menu, Thyroid Peroxidase (TPO) Antibodies (006676), 2026
Tests
Check the catalog code, specimen, method and preparation for every test that measures Thyroid Peroxidase Antibody. Select up to five tests to compare them side by side.
Quest Diagnostics 9 tests
Single-analyte tests
Thyroid Peroxidase Antibodies (TPO) 5081
Serum · Fasting not stated · Turnaround Set up: Mon-Fri (Day shift); Report available: 5 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA)
- Collection
- Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
- Reference notes
- <9 IU/mL
TPO Antibody Endpoint 15116
Serum · Fasting not stated · Turnaround Set up: Tues-Sat; Report available: 2 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA)
- Reference notes
- <9 IU/mL
Panels that include this biomarker
Thyroid Peroxidase and Thyroglobulin Antibodies 7260
2 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA)
- Collection
- Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
- Reference notes
- Thyroid Peroxidase Ab | <9 IU/mL Thyroglobulin Ab | ≤2 IU/mL
ANA Screen,IFA, with Reflex to Titer and Pattern/Sjogren's Panel 2 19880
4 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA) • Immunofluorescence Assay (IFA) • Immunoturbidimetric
- Reference notes
- See individual tests
Chronic Urticaria Panel 1 16440
4 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- See individual tests
- Preparation
- Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw. Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values. Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
- Reference notes
- See individual tests
Chronic Urticaria Panel 2 (Comprehensive) 90123
5 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- See individual tests
- Preparation
- Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw. Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.
- Collection
- Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection).
- Reference notes
- See individual tests
Primary Biliary Cholangitis (PBC) Diagnostic Panel 19876
5 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA)
- Reference notes
- See individual tests
Labcorp 6 tests
Single-analyte tests
Anti-TPO Ab (RDL) 520018
Serum · Fasting not stated · Turnaround 14 - 21 days
Labcorp catalog pageMethod and collection
- Method
- Chemiluminescent Immunoassay
- Collection
- Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Thyroid Peroxidase (TPO) Antibodies 006676
Serum · Fasting not stated · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- Electrochemiluminescence immunoassay (ECLIA) This assay is performed on the Roche cobas instrument in multiple laboratories throughout Labcorp.
- Collection
- If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
- Reference notes
- See table.1 Age | Range (IU/mL) 0 to 6 d | 0−117 7 d to 3 m | 0−47 4 to 11 m | 0−32 1 to 5 y | 0−13 6 to 10 y | 0−18 11 to 19 y | 0−26 >19 y | 0−34
Panels that include this biomarker
Thyroid Antibodies 006684
2 analytes · Serum · Fasting not stated · Turnaround 1 - 3 days
Labcorp catalog pageMethod and collection
- Method
- See individual test descriptions.
ANA 12 Profile, Do All (RDL) 520299
14 analytes · Serum · Fasting not stated · Turnaround 14 - 21 days
Labcorp catalog pageMethod and collection
- Method
- See individual test components.
- Collection
- Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
ANA 12 Plus Profile, Do All (RDL) 520175
17 analytes · Serum · Fasting not stated · Turnaround 14 - 21 days
Labcorp catalog pageMethod and collection
- Method
- ELISA, IFA, Farr RIA, Turbidimetry, CMIA
- Collection
- Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Chronic Urticaria (CU) Evaluation Profile 505805
24 analytes · Serum · Fasting not stated · Turnaround 7 - 10 days
Labcorp catalog pageMethod and collection
- Method
- See individual tests.
- Collection
- CBC+ESR: Invert lavender-top tube eight to 10 times immediately after tube is filled at the time of collection. Other tests: If a red-top tube is used, transfer separated serum to a plastic transport tube.
0 of 5 tests selected
Pick one moreGoals and conditions
We link Thyroid Peroxidase Antibody to these goals and conditions from named guidelines and studies.
Thyroid functionGoal, companion marker
NICE considers measuring TPO antibodies for adults with TSH above the reference range.
HypothyroidismCondition, ICD-10 E03.9, companion marker
NICE considers measuring TPO antibodies once for adults with TSH above the reference range.
Sources
6 tests: codes, specimens, methods, preparation and reference intervals.
Quest Diagnostics test catalog
9 tests: codes, specimens, methods, preparation and reference intervals.
Clinical guideline: Hypothyroidism (companion), Thyroid function (companion)
Labcorp test menu, Thyroid Peroxidase (TPO) Antibodies (006676), 2026
Laboratory catalog: Range: Labcorp, adults over 19
Quest Diagnostics Test Directory, Thyroid Peroxidase Antibodies (TPO) (5081), 2025
Laboratory catalog: Range: Quest, all ages
MedlinePlus, National Library of Medicine
The description at the top of this page.
LOINC 8099-4
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for Thyroid Peroxidase Antibody
Registered studies that measure Thyroid Peroxidase Antibody, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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