Biomarkers · Chemical
T4,Free(Direct)
Thyroxine is also called T4. T4 is a hormone that your thyroid gland makes.
Thyroxine (T4) Test, MedlinePlus, National Library of Medicine
- Primary unit
- ng/dL
- LOINC codes
- 3024-7
- Tests that measure T4,Free(Direct)
- Labcorp 3, Quest Diagnostics 1
Ranges
Compare the reference ranges labs publish with guideline targets, diagnostic cut-offs, study-based ranges and practitioner targets. Move across the rows to check a value against each range, and open a source from the legend. How to read these ranges
T4,Free(Direct), ng/dL
- Lab reference ranges2 labs
All 2 published ranges, with sources
Lab reference ranges
Quest, adults over 200.8 to 1.8 ng/dL
Adults over 20
Quest Diagnostics Test Directory, T4, Free (FT4) (866), 2025
Labcorp, adults over 190.82 to 1.77 ng/dL
Adults over 19
Labcorp test menu, Thyroxine (T4), Free, Direct (001974), 2026
Tests
Check the catalog code, specimen, method and preparation for every test that measures T4,Free(Direct). Select up to five tests to compare them side by side.
Labcorp 3 tests
Single-analyte tests
Thyroxine (T4), Free, Direct 001974
Serum · Fasting not stated · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- Electrochemiluminescence immunoassay (ECLIA) This assay is performed on the Roche cobas instrument in multiple laboratories throughout Labcorp.
- Preparation
- Heparin has been reported to have in vivo and in vitro effects on free T4 assay. Hence samples should not be collected during or soon after the administration of this anticoagulant.
- Collection
- If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
- Reference notes
- See table.1 Age | Range (ng/dL) 0 to 3 d | 0.66−2.71 4 to 30 d | 0.83−3.09 31 d to 12 m | 0.48−2.34 13 m to 5 y | 0.85−1.75 6 to 10 y | 0.90−1.67 11 to 19 y | 0.93−1.60 >19 y | 0.82−1.77
Panels that include this biomarker
Thyroid-stimulating Hormone (TSH) and Free T4 224576
2 analytes · Serum · Fasting not stated · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- Electrochemiluminescence immunoassay (ECLIA)
- Collection
- If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
Long COVID Profile 165065
52 analytes · Serum · Fasting not stated · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- See individual test components.
- Collection
- Serum: Separate serum from cells within two hours of collection. Urine: A voided specimen is usually suitable. If the specimen is likely to be contaminated, a clean catch midstream specimen is desirable. Whole blood: Invert tubes 8 to 10 times immediately after tube is filled at time of collection.
Quest Diagnostics 1 test
Single-analyte tests
T4 Free (FT4) 866
Serum · Fasting not stated · Turnaround Set up: Sun-Fri; Report available: 3 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoassay (IA)
- Reference notes
- <1 Month Not established 1-23 Months 0.9-1.4 ng/dL 2-12 Years 0.9-1.4 ng/dL 13-20 Years 0.8-1.4 ng/dL >20 Years 0.8-1.8 ng/dL
0 of 5 tests selected
Pick one moreGoals and conditions
We link T4,Free(Direct) to these goals and conditions from named guidelines and studies.
Thyroid functionGoal, primary marker
NICE measures free thyroxine in the same sample when TSH is outside the reference range.
HyperthyroidismCondition, ICD-10 E05.90, primary marker
ATA assesses serum TSH, free T4 and total T3 at the initial evaluation when thyrotoxicosis is strongly suspected.
HypothyroidismCondition, ICD-10 E03.9, primary marker
NICE measures free thyroxine in the same sample when TSH is above the reference range.
Sources
3 tests: codes, specimens, methods, preparation and reference intervals.
Quest Diagnostics test catalog
1 test: codes, specimens, methods, preparation and reference intervals.
Clinical guideline: Hyperthyroidism (primary)
Clinical guideline: Hypothyroidism (primary), Thyroid function (primary)
Labcorp test menu, Thyroxine (T4), Free, Direct (001974), 2026
Laboratory catalog: Range: Labcorp, adults over 19
Quest Diagnostics Test Directory, T4, Free (FT4) (866), 2025
Laboratory catalog: Range: Quest, adults over 20
MedlinePlus, National Library of Medicine
The description at the top of this page.
LOINC 3024-7
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for T4,Free(Direct)
Registered studies that measure T4,Free(Direct), on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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