Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

ALT

An ALT test measures the amount of ALT in your blood. This test is commonly used to help diagnose liver damage or disease.

ALT Blood Test, MedlinePlus, National Library of Medicine

Also listed as
alanine transaminase, alanine aminotransferase, sgpt, ALT P5P
Primary unit
IU/L
LOINC codes
1743-4, 1742-6
Tests that measure ALT
Labcorp 24, Quest Diagnostics 19

Ranges

Compare the reference ranges labs publish with guideline targets, diagnostic cut-offs, study-based ranges and practitioner targets. Move across the rows to check a value against each range, and open a source from the legend. How to read these ranges

ALT, U/L

Labs, womenLabs, men
Cut-offs
  • Lab reference ranges1 lab
  • Diagnostic cut-offs2 cut-offs
All 4 published ranges, with sources

Lab reference ranges

Diagnostic cut-offs

Tests

Check the catalog code, specimen, method and preparation for every test that measures ALT. Select up to five tests to compare them side by side.

Labcorp 24 tests

Single-analyte tests

  • Alanine Aminotransferase (ALT/SGPT) 001545

    Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    Kinetic
    Collection
    Separate serum or plasma from cells within 45 minutes of collection.
    Labcorp catalog page

Panels that include this biomarker

  • Drug-Induced Liver Injury Pattern Assessment with Calculation of R Value 010035

    2 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    See individual tests.
    Collection
    Separate serum or plasma from cells within 45 minutes of collection.
    Labcorp catalog page

  • FIB-4 403604

    4 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    AST and ALT: Kinetic Platelet Count: Automated cell counter
    Collection
    Separate serum or plasma from cells within 45 minutes of collection; invert EDTA tube immediately 8 to 10 times once tube is filled at time of collection.
    Reference notes
    0 – 1.29: low risk for advanced liver fibrosis 1.30 – 2.67: Indeterminate risk for advanced liver fibrosis >2.67: high risk for advanced fibrosis and for developing of other liver-related events
    Labcorp catalog page

  • FIB-4 With Reflex to Enhanced Liver Fibrosis (ELF)™ 402175

    4 analytes · Serum · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    AST and ALT: kinetic Platelet Count: automated cell counter ELF Reflex if performed: The ELF™ test consists of three fully automated, two-site sandwich immunoassays using direct chemiluminometric technology. The component assays use two monoclonal mouse antibodies: The first antibody is an acridinium ester-labeled antibody. The second antibody is a biotin-labeled antibody. The solid phase contains streptavidin-coated paramagnetic particles. The ELF™ score is derived from an algorithm that combines PIIINP, TIMP-1, and HA. ELF™ is a trademark of Siemens Healthcare Diagnostics.
    Collection
    Serum : Separate from cells within 45 minutes of collection. Whole blood : Invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.
    Labcorp catalog page

  • FIB-4 With Reflex to NASH FibroSure® Plus 402146

    4 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    See individual test components.
    Preparation
    Patient should be fasting for at least eight hours.
    Collection
    Serum : Separate from cells within 45 minutes of collection. Whole blood : Invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.
    Labcorp catalog page

  • Drug-Induced Liver Injury Profile 010045

    6 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    See individual tests.
    Collection
    Serum or plasma: Separate serum or plasma from cells within 45 minutes of collection. PT with INR blood: Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube. When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
    Labcorp catalog page

Quest Diagnostics 19 tests

Single-analyte tests

  • Alanine Aminotransferase (ALT) 823

    Serum · Fasting not stated · Turnaround Set up: Mon-Sat; Report available: 3 days

    Method and collection
    Method
    Spectrophotometry (SP)
    Preparation
    The assay manufacturer, Beckman Coulter, warns that patients treated with sulfasalazine may generate false low results for ALT.
    Reference notes
    Male (U/L) | Female (U/L) <28 days | 3-25 | 3-25 28 days-11 months | 4-35 | 3-30 1-3 years | 5-30 | 5-30 4-12 years | 8-30 | 8-24 13-15 years | 7-32 | 6-19 16-19 years | 8-46 | 5-32 ≥20 years | 9-46 | 6-29
    Quest Diagnostics catalog page

Panels that include this biomarker

  • FIB-4 Index Panel with Reflex to Enhanced Liver Fibrosis (ELF) Score 12734

    4 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Electronic Cell Sizing/Counting/Cytometry/Microscopy • Spectrophotometry (SP)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Hepatitis C-Infected Patient, Treatment Panel 91706

    4 analytes · Serum · Fasting not stated

    Method and collection
    Method
    See individual tests
    Collection
    Whole blood: 1 full EDTA (lavender-top) tube. Submit at room temperature. Serum: 1 spun serum separator tube (SST). Submit at room temperature. Plasma: Collect 2 EDTA (lavender-top) tubes. Spin and pour off into transport tubes. Submit refrigerated. Do not freeze whole blood or any samples stored in primary tube. Freshly drawn specimens (whole blood) may be stored at 2-25° C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation. Follow manufacturer's instructions for collection tube handling.
    Reference notes
    See individual tests
    Quest Diagnostics catalog page

  • Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel 30555

    4 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy
    Collection
    Note: If drawn with lead testing, EDTA (tan-top) is required
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Hepatic Function Panel without Total Protein 34391

    7 analytes · Serum · Fasting not stated

    Method and collection
    Method
    See individual tests
    Quest Diagnostics catalog page

  • NAFLD Fibrosis Score 91979

    7 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy
    Preparation
    Fasting preferred. Fasting is defined as no consumption of food or beverage other than water for at least 8 hours before testing.
    Collection
    For risk calculations to be performed, the following patient-specific information must be provided at the time of order: Age: Years Gender: M (for male) or F (for female) Height Feet: Feet Height Inches: Inches Weight: lbs. Diabetes Status: Y (for yes) or N (for no)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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Goals and conditions

We link ALT to these goals and conditions from named guidelines and studies.

Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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