Biomarkers · Chemical
LDL Chol Calc
A cholesterol test is a blood test that measures the amount of cholesterol and triglycerides (a type of fat) in your blood. Cholesterol is a waxy, fat-like substance that's found in your blood and every cell of your body.
Cholesterol Levels, MedlinePlus, National Library of Medicine
- Also listed as
- NIH
- Primary unit
- mg/dL
- LOINC codes
- 13457-7, 2089-1
- Tests that measure LDL Chol Calc
- Labcorp 29, Quest Diagnostics 8
Ranges
Compare the reference ranges labs publish with guideline targets, diagnostic cut-offs, study-based ranges and practitioner targets. Move across the rows to check a value against each range, and open a source from the legend. How to read these ranges
LDL Chol Calc, mg/dL
- Lab reference ranges2 labs
- ESC/EAS 2019 targetsbelow 55–116
- AHA/ACC 2018 nonstatin threshold, very high riskbelow 70
- Diagnostic cut-offs2 cut-offs
All 9 published ranges, with sources
Lab reference ranges
Quest, adults 20 and olderbelow 100 mg/dL
Adults 20 and older
Published as below 100 mg/dL (calculated LDL-C).
Quest Diagnostics Test Directory, Lipid Panel, Standard (7600), 2025
Labcorp, adults over 190 to 99 mg/dL
Adults over 19
Labcorp test menu, Low-density Lipoprotein Cholesterol, Direct (120295), 2026
Diagnostic cut-offs
AHA/ACC 2018 severe hypercholesterolemia190 mg/dL and above
Adults
LDL-C of 190 mg/dL (4.9 mmol/L) or higher defines severe primary hypercholesterolemia.
NCEP ATP III, very high190 mg/dL and above
Adults
ATP III classifies LDL-C of 190 mg/dL or higher as very high and 160 to 189 as high. NHLBI marks ATP III as superseded.
Guideline targets
ESC/EAS 2019, very high riskbelow 55 mg/dL
Adults at very high cardiovascular risk
Below 1.4 mmol/L (55 mg/dL) and at least a 50% reduction from baseline.
ESC/EAS 2019, high riskbelow 70 mg/dL
Adults at high cardiovascular risk
Below 1.8 mmol/L (70 mg/dL) and at least a 50% reduction from baseline.
ESC/EAS 2019, moderate riskbelow 100 mg/dL
Adults at moderate cardiovascular risk
Below 2.6 mmol/L (100 mg/dL).
ESC/EAS 2019, low riskbelow 116 mg/dL
Adults at low cardiovascular risk
Below 3.0 mmol/L (116 mg/dL).
AHA/ACC 2018 nonstatin threshold, very high riskbelow 70 mg/dL
Adults with very high-risk ASCVD
At 70 mg/dL (1.8 mmol/L) or higher on statin therapy, the guideline considers adding a nonstatin.
Tests
Check the catalog code, specimen, method and preparation for every test that measures LDL Chol Calc. Select up to five tests to compare them side by side.
Labcorp 29 tests
Panels that include this biomarker
Familial Hypercholesterolemia Lipid Profile With Interpretation 409500
5 analytes · Serum · No fasting · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- See individual tests.
- Preparation
- Patient should be on a stable diet, ideally for two to three weeks prior to collection of blood. Fasting is not necessary for this profile, however, fasting (12 to 14 hours preferred; eight hours acceptable) prior to collection of the specimen is recommended where the triglyceride value provides a prior diagnostic information such as screening for familial hypercholesterolemia or early onset heart disease, pancreatitis, or confirming hypertriglyceridemia.
- Collection
- Separate serum or plasma from cells within 45 minutes of collection. Lipid panels are best avoided for three months following acute myocardial infarction, although cholesterol can be measured in the first 24 hours.
- Reference notes
- See table. Interpretation Age (y) Total Cholesterol (mg/dL) LDL-calculated (mg/dL) FH lipid decision points are age dependent. Consider possible FH if either the Total Cholesterol or LDL-calculated values are exceeded. <16 | >260 | >155 ≥16 | >290 | >190
Lipid Panel 303756
5 analytes · Serum · No fasting · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- See individual tests.
- Preparation
- Patient should be on a stable diet, ideally for two to three weeks prior to collection of blood. Fasting is not necessary for this profile, however, fasting (12 to 14 hours preferred; eight hours acceptable) prior to collection of the specimen is recommended where the triglyceride value provides a prior diagnostic information such as screening for familial hypercholesterolemia or early onset heart disease, pancreatitis, or confirming hypertriglyceridemia.
- Collection
- Separate serum or plasma from cells within 45 minutes of collection. Lipid panels are best avoided for three months following acute myocardial infarction, although cholesterol can be measured in the first 24 hours.
Lipid Profile, Fasting, Pediatric 373632
5 analytes · Serum · Fasting not stated · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- Enzymatic
- Preparation
- Patient should be on stable diet, ideally for two to three weeks prior to collection of blood, and should fast for 12 to 14 hours before collection of the specimen.
- Collection
- Separate serum or plasma or from cells within 45 minutes of collection.
Lipoprotein Phenotyping Profile 235036
5 analytes · Serum · Fasting not stated · Turnaround 5 - 9 days
Labcorp catalog pageMethod and collection
- Method
- Electrophoretic with Frederickson phenotyping criteria
- Preparation
- Patient should be on stable diet, ideally for two to three weeks prior to collection of blood, and should fast for 12 to 14 hours before collection of the specimen.
- Collection
- Separate serum from cells within 45 minutes of collection. Lipid panels are best avoided following acute myocardial infarct, for up to three months, although cholesterol can be measured in the first 24 hours.
- Reference notes
- Normal pattern
PrEP Use Only: Lipid Panel 401423
5 analytes · Serum · No fasting · Turnaround Within 1 day
Labcorp catalog pageMethod and collection
- Method
- Colorimetric; Enzymatic
- Preparation
- Patient should be on a stable diet, ideally for two to three weeks prior to collection of blood. Fasting is not necessary for this profile, however, fasting (12 to 14 hours preferred; eight hours acceptable) prior to collection of the specimen is recommended where the triglyceride value provides a prior diagnostic information such as screening for familial hypercholesterolemia or early onset heart disease, pancreatitis, or confirming hypertriglyceridemia.
- Collection
- Separate serum or plasma from cells within 45 minutes of collection. Lipid panels are best avoided for three months following acute myocardial infarction, although cholesterol can be measured in the first 24 hours.
Quest Diagnostics 8 tests
Panels that include this biomarker
Lipid Panel with Reflex to Direct LDL 14852
6 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Spectrophotometry (SP)
- Preparation
- If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required. The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
- Collection
- Centrifuge within 30-60 minutes following collection
- Reference notes
- Total Cholesterol Male (mg/dL) Female (mg/dL) <20 Years <170 <170 ≥20 Years <200 <200 HDL Cholesterol <20 Years >45 >45 ≥20 Years ≥40 ≥50 Triglycerides ≤9 Years <75 <75 10-19 Years <90 <90 ≥20 Years <150 <150 LDL-Cholesterol (Calc) <20 Years <110 <110 ≥20 Years <100 <100 Cholesterol/HDL Ratio (Calc) <5.0 <5.0 Non-HDL Cholesterol <20 Years <120 <120 ≥20 Years <130 <130
Lipid Panel, Standard 7600
6 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Spectrophotometry (SP)
- Preparation
- If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required. The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
- Reference notes
- Total Cholesterol | Male (mg/dL) | Female (mg/dL) <20 Years | <170 | <170 ≥20 Years | <200 | <200 HDL Cholesterol <20 Years | >45 | >45 ≥20 Years | ≥40 | ≥50 Triglycerides ≤9 Years | <75 | <75 10-19 Years | <90 | <90 ≥20 Years | <150 | <150 LDL-Cholesterol (calc) <20 Years | <110 | <110 ≥20 Years | <100 | <100 Cholesterol/HDL Ratio (calc) | <5.0 | <5.0 Non-HDL Cholesterol (calc) <20 Years | <120 | <120 ≥20 Years | <130 | <130
Lipoprotein Fractionation Ultracentrifugation 36435
6 analytes · Serum · Fasting not stated · Turnaround Set up: Mon-Fri (a.m.); Report available: 7 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Ultracentrifugation • Colorimetric • Enzymatic
- Preparation
- If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required. The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
- Collection
- Pleural fluid is not an acceptable specimen type
- Reference notes
- See Laboratory Report
ASCVD Risk Panel with Score 92053
7 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Enzymatic • Spectrophotometry (SP)
- Preparation
- If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required. The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
- Collection
- For risk calculations to be performed, the following patient specific information have to be provided at time of order: Age: Years Gender: M (for male) or F (for female) Race-African American: Y (for yes) or N (for no) Systolic Blood Pressure: mmHg Treatment for High Blood Pressure: Y (for yes) or N (for no) Diabetes Status: Y (for yes) or N (for no) Smoking Status: Y (for Yes) or N (for no)
- Reference notes
- Total Cholesterol | Male (mg/dL) | Female (mg/dL) <20 Years | <170 | <170 ≥20 Years | <200 | <200 HDL Cholesterol <20 Years | >45 | >45 ≥20 Years | ≥40 | ≥50 Triglycerides ≤9 Years | <75 | <75 10-19 Years | <90 | <90 ≥20 Years | <150 | <150 LDL-Cholesterol (Calc) <20 Years | <110 | <110 ≥20 Years | <100 | <100 Cholesterol/HDL Ratio (Calc) | <5.0 | <5.0 Non-HDL Cholesterol <20 Years | <120 | <120 ≥20 Years | <130 | <130 ASCVD Risk Scores | See Laboratory Report
Lipid Panel with Ratios 19543
7 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Spectrophotometry (SP)
- Preparation
- If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required. The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
- Collection
- Centrifuge within 30-60 minutes following collection
- Reference notes
- Total Cholesterol Male (mg/dL) Female (mg/dL) <20 Years <170 <170 ≥20 Years <200 <200 HDL Cholesterol <20 Years >45 >45 ≥20 Years ≥40 ≥50 Triglycerides ≤9 Years <75 <75 10-19 Years <90 <90 ≥20 Years <150 <150 LDL-Cholesterol (Calc) <20 Years <110 <110 ≥20 Years <100 <100 Cholesterol/HDL Ratio (Calc) <5.0 <5.0 LDL/HDL Ratio (Calc) Below Average Risk <2.28 <2.34 Average Risk 2.29-4.90 2.35-4.12 Moderate Risk 4.91-7.12 4.13-5.56 High Risk >7.13 >5.57 Non-HDL Cholesterol <20 Years <120 <120 ≥20 Years <130 <130
0 of 5 tests selected
Pick one moreGoals and conditions
We link LDL Chol Calc to these goals and conditions from named guidelines and studies.
Heart healthGoal, primary marker
The AHA/ACC guideline uses LDL-C thresholds, such as 190 mg/dL and 70 mg/dL, to guide treatment.
HypercholesterolemiaCondition, ICD-10 E78.00, primary marker
The AHA/ACC guideline defines severe primary hypercholesterolemia as LDL-C of 190 mg/dL or higher.
Sources
29 tests: codes, specimens, methods, preparation and reference intervals.
Quest Diagnostics test catalog
8 tests: codes, specimens, methods, preparation and reference intervals.
Clinical guideline: Heart health (primary), Hypercholesterolemia (primary), Range: AHA/ACC 2018 nonstatin threshold, very high risk, Range: AHA/ACC 2018 severe hypercholesterolemia
Clinical guideline: Range: ESC/EAS 2019, high risk, Range: ESC/EAS 2019, low risk, Range: ESC/EAS 2019, moderate risk, Range: ESC/EAS 2019, very high risk
Clinical guideline: Range: NCEP ATP III, very high
Labcorp test menu, Low-density Lipoprotein Cholesterol, Direct (120295), 2026
Laboratory catalog: Range: Labcorp, adults over 19
Quest Diagnostics Test Directory, Lipid Panel, Standard (7600), 2025
Laboratory catalog: Range: Quest, adults 20 and older
MedlinePlus, National Library of Medicine
The description at the top of this page.
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for LDL Chol Calc
Registered studies that measure LDL Chol Calc, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
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